Home > STA/BST 290 Seminar: Patrice Koehl (Dept Computer Science/Genome Center, UC Davis)
Submitted by pscully on Thu, 10/27/2011 - 13:40.
11/03/2011 - 16:10
11/03/2011 - 17:30
Short Title: 
STA/BST 290: Patrice Koehl (UC Davis)
Short Desc: 
Protein structure and sequence spaces: how big are they?

Department of Statistics

Graduate Group in Biostatistics

University of California, Davis

 

STATISTICS COLLOQUIUM

 

 

 

Thursday, November 3rd, 2011 at 4.10pm, MSB 1147 (Colloquium Room)

Refreshments: 3.30pm, MSB 4110 (Statistics Lounge)

 

 

Speaker:   Patrice Koehl (Dept Computer Science/Genome Center, UC Davis)

 

Title:        Protein structure and sequence spaces: how big are they?

             

Abstract: Gene family and protein structure family sizes are known to vary widely, from orphans to considerably populated sets of far-diverged homologs.

The underlying causes behind these observed irregularities in sequence space remain unclear. In this seminar, I will show that geometry and thermodynamics are key elements for measuring the ability of a protein to accept mutations without losing its structure.

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